Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ddrgk1tm1b(EUCOMM)Hmgu targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH MGI:5692746 |
||||||||||||
| Summary |
2 genotypes
|
|
|
Data Sources
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• most mice died at E12.5 and all mice are dead by E13.5
|
|
• reduced colony-forming units-granulocyte/macrophage and colony-forming units-granulocyte/erythrocyte/macrophage/megakaryocyte in E11.5 fetal livers
|
|
• in E8.5 yolk sac
|
|
• fewer peripheral circulating erythrocytes at E11.5
|
|
• large number of abnormal multinucleated erythroid cells with some exhibiting cell death
|
|
• impaired with a blocked differentiation of TER1119low into TER119med+high cells
|
|
• extensive in the brain (fourth ventricle at E11.5), liver and other tissues (duodenum lumen at E11.5)
|
|
• most mice died at E12.5 and all mice are dead by E13.5
|
|
• impaired with a blocked differentiation of TER1119low into TER119med+high cells
|
|
• most mice died at E12.5 and all mice are dead by E13.5
|
|
• small and disorganized with reduced cellularity and increased cell death at E11.5
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 10/29/2024 MGI 6.24 |
|
|
|
||
