All Phenotypes Otub1<tm1b(EUCOMM)Hmgu> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Otub1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5692787

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757462
hm2	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics	MGI:5757461
ht3	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757460
ht4	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics	MGI:6461504

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - HAR

cardiovascular system

abnormal heart position or orientation ( J:211773 )

IMPC - HAR

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - HAR

respiratory system

abnormal lung morphology ( J:211773 )

IMPC - HAR

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - HAR

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - ICS

skeleton

decreased bone mineral content ( J:211773 )

IMPC - ICS

vision/eye

increased cornea thickness ( J:211773 )

IMPC - ICS

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24