All Phenotypes Otub1<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Otub1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5692787

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757462
hm2	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics	MGI:5757461
ht3	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757460
ht4	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics	MGI:6461504

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - HAR

cardiovascular system

abnormal heart position or orientation ( J:211773 )

IMPC - HAR

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - HAR

respiratory system

abnormal lung morphology ( J:211773 )

IMPC - HAR

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - HAR

Allelic Composition	Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺
Genetic Background	C57BL/6N-Otub1^{tm1b(EUCOMM)Hmgu}/Ics
Cell Lines	HEPD0539_8_A05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otub1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Otub1 mutation (27 available)

Data Sources

IMPC Data for Otub1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - ICS

skeleton

decreased bone mineral content ( J:211773 )

IMPC - ICS

vision/eye

increased cornea thickness ( J:211773 )

IMPC - ICS

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