Phenotypes associated with this allele

• Allele Symbol: Ift172^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5692847
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ift172^tm2b(EUCOMM)Hmgu/Ift172^tm2b(EUCOMM)Hmgu	C57BL/6N-Ift172^tm2b(EUCOMM)Hmgu/Bay	MGI:6262673
ht2	Ift172^tm2b(EUCOMM)Hmgu/Ift172^+	C57BL/6N-Ift172^tm2b(EUCOMM)Hmgu/Bay	MGI:6262672

Genotype
MGI:6262673

hm1

• Allelic Composition: Ift172^{tm2b(EUCOMM)Hmgu}/Ift172^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ift172^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0797_8_B05

Data Sources

IMPC Data for Ift172

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - BCM

abnormal pericardium morphology ( J:211773 )

IMPC - BCM

hemorrhage ( J:211773 )

IMPC - BCM

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

abnormal embryo development ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

IMPC - BCM

abnormal allantois morphology ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

homeostasis/metabolism

edema ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - BCM

Genotype
MGI:6262672

ht2

• Allelic Composition: Ift172^{tm2b(EUCOMM)Hmgu}/Ift172⁺
• Genetic Background: C57BL/6N-Ift172^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0797_8_B05

Data Sources

IMPC Data for Ift172

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - BCM

limbs/digits/tail

abnormal digit morphology ( J:211773 )

♀

IMPC - BCM

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - BCM