Phenotypes associated with this allele

• Allele Symbol: Col11a2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5692880
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col11a2^tm1b(KOMP)Wtsi/Col11a2^tm1b(KOMP)Wtsi	C57BL/6N-Col11a2^tm1b(KOMP)Wtsi/Ieg	MGI:7266991
ht2	Col11a2^tm1b(KOMP)Wtsi/Col11a2^+	C57BL/6N-Col11a2^tm1b(KOMP)Wtsi/Ieg	MGI:6262185

Genotype
MGI:7266991

hm1

• Allelic Composition: Col11a2^{tm1b(KOMP)Wtsi}/Col11a2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Col11a2^{tm1b(KOMP)Wtsi}/Ieg
• Cell Lines: EPD0898_3_F06

Data Sources

IMPC Data for Col11a2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262185

ht2

• Allelic Composition: Col11a2^{tm1b(KOMP)Wtsi}/Col11a2⁺
• Genetic Background: C57BL/6N-Col11a2^{tm1b(KOMP)Wtsi}/Ieg
• Cell Lines: EPD0898_3_F06

Data Sources

IMPC Data for Col11a2

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - HMGU

cardiovascular system

decreased cardiac output ( J:211773 )

♀

IMPC - HMGU

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - HMGU

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - HMGU

increased circulating unsaturated transferrin level ( J:211773 )

♀

IMPC - HMGU