Phenotypes associated with this allele

• Allele Symbol: Gjb3^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5692890
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gjb3^tm1.1(KOMP)Vlcg/Gjb3^tm1.1(KOMP)Vlcg	C57BL/6N-Gjb3^tm1.1(KOMP)Vlcg/Ucd	MGI:5785076
ht2	Gjb3^tm1.1(KOMP)Vlcg/Gjb3^+	C57BL/6N-Gjb3^tm1.1(KOMP)Vlcg/Ucd	MGI:5797558

Genotype
MGI:5785076

hm1

• Allelic Composition: Gjb3^{tm1.1(KOMP)Vlcg}/Gjb3^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Gjb3^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 15368A-A7

Data Sources

IMPC Data for Gjb3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - UCD

cleft palate ( J:211773 )

IMPC - UCD

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal embryo size ( J:211773 )

IMPC - UCD

growth/size/body

cleft palate ( J:211773 )

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal embryo size ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

integument

abnormal skin appearance ( J:211773 )

IMPC - UCD

pallor ( J:211773 )

IMPC - UCD

abnormal skin coloration ( J:211773 )

IMPC - UCD

liver/biliary system

pale liver ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:5797558

ht2

• Allelic Composition: Gjb3^{tm1.1(KOMP)Vlcg}/Gjb3⁺
• Genetic Background: C57BL/6N-Gjb3^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 15368A-A7

Data Sources

IMPC Data for Gjb3

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

increased mean corpuscular volume ( J:211773 )

♀

IMPC - UCD