All Phenotypes Notch1<tm1b(EUCOMM)Hmgu> MGI Mouse

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Notch1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5692906

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Notch1^{tm1b(EUCOMM)Hmgu}/Notch1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Notch1^{tm1b(EUCOMM)Hmgu}/H	MGI:5767742
ht2	Notch1^{tm1b(EUCOMM)Hmgu}/Notch1⁺	C57BL/6N-Notch1^{tm1b(EUCOMM)Hmgu}/H	MGI:6263036

Allelic Composition	Notch1^{tm1b(EUCOMM)Hmgu}/Notch1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Notch1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0627_7_B12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Notch1 mutation (115 available)

Data Sources

IMPC Data for Notch1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Notch1^{tm1b(EUCOMM)Hmgu}/Notch1⁺
Genetic Background	C57BL/6N-Notch1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0627_7_B12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Notch1 mutation (115 available)

Data Sources

IMPC Data for Notch1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased startle reflex ( J:211773 )

IMPC - HAR

increased grip strength ( J:211773 )

IMPC - HAR

skeleton

abnormal vertebrae morphology ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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