All Phenotypes Hdac6<tm1.1Tyao> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hdac6^tm1.1Tyao
targeted mutation 1.1, Tso-Pang Yao
MGI:5693117

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hdac6^tm1.1Tyao/Hdac6^tm1.1Tyao	involves: 129S6/SvEvTac * FVB/N	MGI:5693159

Allelic Composition	Hdac6^tm1.1Tyao/Hdac6^tm1.1Tyao
Genetic Background	involves: 129S6/SvEvTac * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdac6^tm1.1Tyao mutation (0 available); any Hdac6 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell migration ( J:128914 )

• mouse embryonic fibroblasts (MEFs) exhibit impaired membrane ruffle formation, macropinocytosis and cell migration

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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