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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm2(Sp8)Lma
targeted mutation 2, Liang Ma
MGI:5694150
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Sp8tm1Smb/Sp8tm1Smb
Tg(Msx2-cre)5Rem/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA MGI:5694217
cn2
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Tg(Msx2-cre)5Rem/0
involves: 129X1/SvJ * C57BL/6 * CBA MGI:5694224
cn3
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Tg(Msx2-cre)5Rem/0
involves: C57BL/6 * CBA MGI:5694223
cn4
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
Not Specified MGI:5694220


Genotype
MGI:5694217
cn1
Allelic
Composition
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Sp8tm1Smb/Sp8tm1Smb
Tg(Msx2-cre)5Rem/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(Sp8)Lma mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Sp8tm1Smb mutation (0 available); any Sp8 mutation (29 available)
Tg(Msx2-cre)5Rem mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5694224
cn2
Allelic
Composition
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Tg(Msx2-cre)5Rem/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (49 available)
Gt(ROSA)26Sortm2(Sp8)Lma mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Tg(Msx2-cre)5Rem mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• mice exhibit normal appendage development




Genotype
MGI:5694223
cn3
Allelic
Composition
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Tg(Msx2-cre)5Rem/0
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(Sp8)Lma mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Tg(Msx2-cre)5Rem mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• mice exhibit normal appendage development




Genotype
MGI:5694220
cn4
Allelic
Composition
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(Sp8)Lma mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Shhtm1(EGFP/cre)Cjt mutation (1 available); any Shh mutation (48 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• mice exhibit normal appendage development





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory