Phenotypes associated with this allele

• Allele Symbol: Lta^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5695877
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lta^tm1.1(KOMP)Vlcg/Lta^tm1.1(KOMP)Vlcg	C57BL/6N-Lta^tm1.1(KOMP)Vlcg/MbpMmucd	MGI:6461414
hm2	Lta^tm1.1(KOMP)Vlcg/Lta^tm1.1(KOMP)Vlcg	C57BL/6N-Lta^tm1.1(KOMP)Vlcg/Ucd	MGI:5706033

Genotype
MGI:6461414

hm1

• Allelic Composition: Lta^{tm1.1(KOMP)Vlcg}/Lta^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Lta^{tm1.1(KOMP)Vlcg}/MbpMmucd
• Cell Lines: 12792A-B9

Data Sources

IMPC Data for Lta

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased bronchoconstrictive response ( J:211773 )

♂

IMPC - TCP

respiratory system

increased bronchoconstrictive response ( J:211773 )

♂

IMPC - TCP

increased pulmonary ventilation ( J:211773 )

♂

IMPC - TCP

Genotype
MGI:5706033

hm2

• Allelic Composition: Lta^{tm1.1(KOMP)Vlcg}/Lta^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Lta^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 12792A-B9

Data Sources

IMPC Data for Lta

growth/size/body

decreased body length ( J:211773 )

♀

IMPC - UCD

hematopoietic system

decreased monocyte cell number ( J:211773 )

IMPC - UCD

increased leukocyte cell number ( J:211773 )

IMPC - UCD

increased eosinophil cell number ( J:211773 )

♀

IMPC - UCD

increased neutrophil cell number ( J:211773 )

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

IMPC - UCD

immune system

decreased monocyte cell number ( J:211773 )

IMPC - UCD

increased leukocyte cell number ( J:211773 )

IMPC - UCD

increased eosinophil cell number ( J:211773 )

♀

IMPC - UCD

increased neutrophil cell number ( J:211773 )

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

IMPC - UCD