Phenotypes associated with this allele

• Allele Symbol: Folr1^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5695973
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Folr1^tm1.1(KOMP)Vlcg/Folr1^tm1.1(KOMP)Vlcg	C57BL/6N-Folr1^tm1.1(KOMP)Vlcg/Tcp	MGI:5767669
ht2	Folr1^tm1.1(KOMP)Vlcg/Folr1^+	C57BL/6N-Folr1^tm1.1(KOMP)Vlcg/Tcp	MGI:5797543

Genotype
MGI:5767669

hm1

• Allelic Composition: Folr1^{tm1.1(KOMP)Vlcg}/Folr1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Folr1^{tm1.1(KOMP)Vlcg}/Tcp
• Cell Lines: 19773A-F3

Data Sources

IMPC Data for Folr1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:5797543

ht2

• Allelic Composition: Folr1^{tm1.1(KOMP)Vlcg}/Folr1⁺
• Genetic Background: C57BL/6N-Folr1^{tm1.1(KOMP)Vlcg}/Tcp
• Cell Lines: 19773A-F3

Data Sources

IMPC Data for Folr1

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - UCD

increased heart atrium size ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

small testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

IMPC - UCD

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - UCD

abnormal cholesterol homeostasis ( J:211773 )

♀

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

reproductive system

small testis ( J:211773 )

♂

IMPC - UCD