Phenotypes associated with this allele

• Allele Symbol: Notch3^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5695981
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Notch3^tm1.1(KOMP)Vlcg/Notch3^tm1.1(KOMP)Vlcg	C57BL/6N-Notch3^tm1.1(KOMP)Vlcg/Ucd	MGI:5706050

Genotype
MGI:5706050

hm1

• Allelic Composition: Notch3^{tm1.1(KOMP)Vlcg}/Notch3^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Notch3^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 18699A-D7

Data Sources

IMPC Data for Notch3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - UCD

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

increased kidney weight ( J:211773 )

♂

IMPC - UCD

increased spleen weight ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased spleen weight ( J:211773 )

♂

IMPC - UCD

increased red blood cell distribution width ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

improved glucose tolerance ( J:211773 )

♂

IMPC - UCD

immune system

increased spleen weight ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

liver/biliary system

decreased liver weight ( J:211773 )

♂

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

increased kidney weight ( J:211773 )

♂

IMPC - UCD