Phenotypes associated with this allele

• Allele Symbol: b2b1702Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 1702 Cecilia Lo
• Allele ID: MGI:5696518
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	b2b1702Clo/b2b1702Clo	C57BL/6J-b2b1702Clo	MGI:5696651

Genotype
MGI:5696651

hm1

• Allelic Composition: b2b1702Clo/b2b1702Clo
• Genetic Background: C57BL/6J-b2b1702Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1702-003-2 (E16.5) displays malaligned great arteries indicative of double outlet right ventricle (DORV) as confirmed by ECM imaging.

cardiovascular system

coronary fistula ( J:175213 )

double outlet right ventricle ( J:175213 )

double outlet right ventricle, Taussig bing type ( J:175213 )

double outlet right ventricle, ventricular defect committed to aorta ( J:175213 )

transposition of great arteries ( J:175213 )

dextrocardia ( J:175213 )

mesocardia ( J:175213 )

atrioventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

increased heart ventricle size ( J:175213 )

• biventricular hypertrophy

respiratory system

right pulmonary isomerism ( J:175213 )

abnormal lung lobe morphology ( J:175213 )

• 2 lobes on right/1 lobe on left

growth/size/body

cleft palate ( J:175213 )

short snout ( J:175213 )

herniated abdominal wall ( J:175213 )

omphalocele ( J:175213 )

decreased body size ( J:175213 )

heterotaxia ( J:175213 )

right-sided stomach ( J:175213 )

right pulmonary isomerism ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

right-sided stomach ( J:175213 )

vision/eye

microphthalmia ( J:175213 )

anophthalmia ( J:175213 )

craniofacial

micrognathia ( J:175213 )

cleft palate ( J:175213 )

short snout ( J:175213 )

homeostasis/metabolism

hydrops fetalis ( J:175213 )

skeleton

micrognathia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

spleen hypoplasia ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

spleen hypoplasia ( J:175213 )

integument

petechiae ( J:175213 )