Phenotypes associated with this allele

• Allele Symbol: Tdo2^{tm1b(KOMP)Mbp}
• Allele Name: targeted mutation 1b, Mouse Biology Program, UC Davis
• Allele ID: MGI:5696916
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tdo2^tm1b(KOMP)Mbp/Tdo2^tm1b(KOMP)Mbp	C57BL/6N-Tdo2^tm1b(KOMP)Mbp/Tcp	MGI:6288766
ht2	Tdo2^tm1b(KOMP)Mbp/Tdo2^+	C57BL/6N-Tdo2^tm1b(KOMP)Mbp/Tcp	MGI:6288765

Genotype
MGI:6288766

hm1

• Allelic Composition: Tdo2^{tm1b(KOMP)Mbp}/Tdo2^{tm1b(KOMP)Mbp}
• Genetic Background: C57BL/6N-Tdo2^{tm1b(KOMP)Mbp}/Tcp
• Cell Lines: DEPD0006_13_H07

Data Sources

IMPC Data for Tdo2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

♀

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:6288765

ht2

• Allelic Composition: Tdo2^{tm1b(KOMP)Mbp}/Tdo2⁺
• Genetic Background: C57BL/6N-Tdo2^{tm1b(KOMP)Mbp}/Tcp
• Cell Lines: DEPD0006_13_H07

Data Sources

IMPC Data for Tdo2

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

increased heart weight ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

increased heart weight ( J:211773 )

♂

IMPC - UCD

nervous system

increased prepulse inhibition ( J:211773 )

IMPC - UCD