Phenotypes associated with this allele

• Allele Symbol: Pi4ka^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5696927
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pi4ka^tm1b(EUCOMM)Wtsi/Pi4ka^tm1b(EUCOMM)Wtsi	C57BL/6N-Pi4ka^tm1b(EUCOMM)Wtsi/Tcp	MGI:6263159
ht2	Pi4ka^tm1b(EUCOMM)Wtsi/Pi4ka^+	C57BL/6N-Pi4ka^tm1b(EUCOMM)Wtsi/Tcp	MGI:6461527

Genotype
MGI:6263159

hm1

• Allelic Composition: Pi4ka^{tm1b(EUCOMM)Wtsi}/Pi4ka^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Pi4ka^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0619_5_F12

Data Sources

IMPC Data for Pi4ka

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6461527

ht2

• Allelic Composition: Pi4ka^{tm1b(EUCOMM)Wtsi}/Pi4ka⁺
• Genetic Background: C57BL/6N-Pi4ka^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0619_5_F12

Data Sources

IMPC Data for Pi4ka

behavior/neurological

limb grasping ( J:211773 )

♀

IMPC - UCD

hematopoietic system

increased erythrocyte cell number ( J:211773 )

IMPC - UCD

increased hematocrit ( J:211773 )

♀

IMPC - UCD

increased monocyte cell number ( J:211773 )

♀

IMPC - UCD

immune system

increased monocyte cell number ( J:211773 )

♀

IMPC - UCD