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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
D130043K22Riktm1b(KOMP)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5696928
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
D130043K22Riktm1b(KOMP)Wtsi/D130043K22Riktm1b(KOMP)Wtsi C57BL/6N-D130043K22Riktm1b(KOMP)Wtsi/Ucd MGI:6262244
hm2
D130043K22Riktm1b(KOMP)Wtsi/D130043K22Riktm1b(KOMP)Wtsi involves: C57BL/6 * CBA MGI:6112643
ht3
D130043K22Riktm1b(KOMP)Wtsi/D130043K22Rik+ involves: C57BL/6 * CBA MGI:6112644


Genotype
MGI:6262244
hm1
Allelic
Composition
D130043K22Riktm1b(KOMP)Wtsi/D130043K22Riktm1b(KOMP)Wtsi
Genetic
Background
C57BL/6N-D130043K22Riktm1b(KOMP)Wtsi/Ucd
Cell Lines EPD0077_5_D04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
D130043K22Riktm1b(KOMP)Wtsi mutation (1 available); any D130043K22Rik mutation (57 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system




Genotype
MGI:6112643
hm2
Allelic
Composition
D130043K22Riktm1b(KOMP)Wtsi/D130043K22Riktm1b(KOMP)Wtsi
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
D130043K22Riktm1b(KOMP)Wtsi mutation (1 available); any D130043K22Rik mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal activity in 1-hour open field test
• normal social interaction and response to social novelty in 3-chamber apparatus
• normal locomotor behavior and motor coordination and balance
• normal spatial learning, working memory and reference memory
• normal learning, memory and conditioning
• spending more time in light area in light/dark box test

cellular
N
• normal cell cycle and mitosis in embryonic brain at E15.5 and E18.5

nervous system
N
• normal radial glial cell number in brain at E15.5 and E18.5
• normal cortical wall thickness in telencephalon at E18.5
• normal telencephalon, cortical plate, dentate gyrus and hippocampus CA1 region morphology at P2 and P10
• normal cerebellum morphology at E15.5, E18.5 and P10
• normal prepulse inibition in females
• in startle responses at long intervals between prepulse and acoustic startle-eliciting stimulus
• normal prepulse inibition in females




Genotype
MGI:6112644
ht3
Allelic
Composition
D130043K22Riktm1b(KOMP)Wtsi/D130043K22Rik+
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
D130043K22Riktm1b(KOMP)Wtsi mutation (1 available); any D130043K22Rik mutation (57 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• activity in 1-hour open field test
• social interaction and response to social novelty in 3-chamber apparatus
• locomotor behavior and motor coordination and balance
• spatial learning, working memory and reference memory
• learning, memory and conditioning
• anxiety related response

nervous system
N
• radial glial cell number in brain at E15.5 and E18.5
• cortical wall thickness in telencephalon at E18.5
• telencephalon, cortical plate, dentate gyrus and hippocampus CA1 region morphology at P2 and P10
• cerebellum morphology at E15.5, E18.5 and P10
• prepulse inibition

cellular
N
• cell cycle and mitosis in embryonic brain at E15.5 and E18.5





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory