Phenotypes associated with this allele

• Allele Symbol: Alg1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5698866
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Alg1^tm1b(KOMP)Wtsi/Alg1^tm1b(KOMP)Wtsi	C57BL/6N-Alg1^tm1b(KOMP)Wtsi/Nju	MGI:6261840
ht2	Alg1^tm1b(KOMP)Wtsi/Alg1^+	C57BL/6N-Alg1^tm1b(KOMP)Wtsi/Nju	MGI:5797355

Genotype
MGI:6261840

hm1

• Allelic Composition: Alg1^{tm1b(KOMP)Wtsi}/Alg1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Alg1^{tm1b(KOMP)Wtsi}/Nju
• Cell Lines: EPD0356_2_C06

Data Sources

IMPC Data for Alg1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - MARC

Genotype
MGI:5797355

ht2

• Allelic Composition: Alg1^{tm1b(KOMP)Wtsi}/Alg1⁺
• Genetic Background: C57BL/6N-Alg1^{tm1b(KOMP)Wtsi}/Nju
• Cell Lines: EPD0356_2_C06

Data Sources

IMPC Data for Alg1

hematopoietic system

increased leukocyte cell number ( J:211773 )

♀

IMPC - MARC

increased basophil cell number ( J:211773 )

♀

IMPC - MARC

increased eosinophil cell number ( J:211773 )

♀

IMPC - MARC

increased lymphocyte cell number ( J:211773 )

♀

IMPC - MARC

homeostasis/metabolism

abnormal cholesterol homeostasis ( J:211773 )

♀

IMPC - MARC

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - MARC

increased basophil cell number ( J:211773 )

♀

IMPC - MARC

increased eosinophil cell number ( J:211773 )

♀

IMPC - MARC

increased lymphocyte cell number ( J:211773 )

♀

IMPC - MARC

integument

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - MARC

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♂

IMPC - MARC