Analysis Tools
behavior/neurological
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• increase in net food intake in calorimetry chamber is observed in mice after 12 weeks on high fat diet
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growth/size/body
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• increase in weight after 24 hours in calorimetry chamber is observed in mice after 12 weeks on high fat diet
• however, body weight at the end of the study is slightly, but not significantly, decreased as compared to controls
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homeostasis/metabolism
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• is observed in male mice on high fat diet (60%) as compared to controls
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• decreased serum cholesterol in males fed high fat diet
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• decreased HDL in males fed high fat diet
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• decreased LDL in males fed high fat diet
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• increased resting energy expenditure is observed in mice on high fat diet
• increase is not due to increased activity
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• improved glucose tolerance is observed in male mice on high fat diet (60%) as compared to controls
• females exhibit a trend for improved tolerance
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• improved insulin tolerance is observed in male mice on high fat diet (60%)
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• increased serum adiponectin in males fed high fat diet
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• triglycerides are reduced in VLDL fraction of sera analyzed by FPLC chromatography
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• males fed high fat diet exhibit a trend for increased liver triglycerides
• however, total triglyceride levels are similar to controls
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liver/biliary system
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• triglycerides are reduced in VLDL fraction of sera analyzed by FPLC chromatography
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• males fed high fat diet exhibit a trend for increased liver triglycerides
• however, total triglyceride levels are similar to controls
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