reproductive system
N |
• female mice exhibit normal fertility
|
• mice exhibit germ cell aggregates from P28 onward in the seminiferous tubules unlike wild-type mice
|
azoospermia
(
J:226405
)
• neither round spermatids nor spermatozoa in adult testes
|
• spermatocytes exhibit aberrant progression through prophase I
• chromosome alignment is abnormal
• however, synaptonemal complex formation and meiotic sex chromosome inactivation are normal
|
• at pachytene stage
|
small testis
(
J:226405
)
|
• from P28 onwards
|
cellular
N |
• male mice exhibit no variation in the expression of retrotransposons in testes
|
• mice exhibit germ cell aggregates from P28 onward in the seminiferous tubules unlike wild-type mice
|
azoospermia
(
J:226405
)
• neither round spermatids nor spermatozoa in adult testes
|
• spermatocytes exhibit aberrant progression through prophase I
• chromosome alignment is abnormal
• however, synaptonemal complex formation and meiotic sex chromosome inactivation are normal
|
• at pachytene stage
|
endocrine/exocrine glands
small testis
(
J:226405
)
|
• from P28 onwards
|