Allele Symbol Allele Name Allele ID |
Mir182tm1.1Dgk targeted mutation 1.1, David Kirsch MGI:5702430 |
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Summary |
3 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• 13% of mice develop lung metastases within 6 months following amputation of limb injected with cre-expressing adenovirus
• in the absence of the Mir18tm1.1Dgk allele, 43% of mice develop lung metastases
• number of metastatic nodules and metastatic burden in the lung are decreased compared to mice without the Mir18tm1.1Dgk allele
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• 20% of mice develop lung metastases by 120 days following amputation of limb injected with cre-expressing adenovirus
• in the absence of the Mir18tm1.1Dgk allele, 43% of mice develop lung metastases
• number of metastatic nodules and metastatic burden in the lung are decreased compared to mice without the Mir18tm1.1Dgk allele
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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