About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Trp63m1Mhda
mutation 1, Martin Hrabe de Angelis
MGI:5702898
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Trp63m1Mhda/Trp63m1Mhda C3HeB/FeJ-Trp63m1Mhda MGI:5702915
ht2
Trp63m1Mhda/Trp63+ C3HeB/FeJ-Trp63m1Mhda MGI:5702913


Genotype
MGI:5702915
hm1
Allelic
Composition
Trp63m1Mhda/Trp63m1Mhda
Genetic
Background
C3HeB/FeJ-Trp63m1Mhda
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp63m1Mhda mutation (1 available); any Trp63 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• "Darth Vader-like" appearance observed at embryonic day (E) 15

limbs/digits/tail

mortality/aging




Genotype
MGI:5702913
ht2
Allelic
Composition
Trp63m1Mhda/Trp63+
Genetic
Background
C3HeB/FeJ-Trp63m1Mhda
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp63m1Mhda mutation (1 available); any Trp63 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice heterozygous for this mutation are viable and exhibit no obvious abnormality





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory