Phenotypes associated with this allele

• Allele Symbol: Gabrb1^m2Qnma
• Allele Name: mutation 2, Quentin M Anstee
• Allele ID: MGI:5704359
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gabrb1^m2Qnma/Gabrb1^+	involves: BALB/cAnN * C3H/HeH	MGI:5704368

Genotype
MGI:5704368

ht1

• Allelic Composition: Gabrb1^m2Qnma/Gabrb1⁺
• Genetic Background: involves: BALB/cAnN * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal corpus luteum morphology ( J:223500 )

• underdeveloped

female infertility ( J:223500 )

homeostasis/metabolism

decreased growth hormone level ( J:223500 )

• in the pituitary

decreased prolactin level ( J:223500 )

• in the pituitary

behavior/neurological

alcohol preference ( J:223500 )

nervous system

abnormal single cell response ( J:223500 )

• nucleus accumbens medium spiny neurons exhibit enhanced tonic conductance compared with wild-type cells

abnormal miniature inhibitory postsynaptic currents ( J:223500 )

• nucleus accumbens medium spiny neurons exhibit reduced miniature inhibitory postsynaptic currents frequency and prolonged decay time compared to in wild-type cells

growth/size/body

decreased body size ( J:223500 )

• not as pronounced as in Gabrb1^m1Qnma heterozygotes

endocrine/exocrine glands

abnormal corpus luteum morphology ( J:223500 )

• underdeveloped