All Phenotypes Slit2<tm1.1Ics> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slit2^tm1.1Ics
targeted mutation 1.1, Mouse Clinical Institute
MGI:5705113

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Slit2^tm1.1Ics/Slit2^tm1.1Ics	involves: 129S2/SvPas * C57BL/6 * CD-1	MGI:5705335
cn2	Slit2^tm1.1Ics/Slit2^tm1.1Ics Tg(Pcp2-cre)2Mpin/?	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1	MGI:5705339

Allelic Composition	Slit2^tm1.1Ics/Slit2^tm1.1Ics
Genetic Background	involves: 129S2/SvPas * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slit2^tm1.1Ics mutation (0 available); any Slit2 mutation (88 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal Purkinje cell dendrite morphology ( J:221288 )

• brain injections of rAAV8 virus expressing cre

• 5 fold increase in overlaps of Purkinji Cell dendritic branches

Allelic Composition	Slit2^tm1.1Ics/Slit2^tm1.1Ics Tg(Pcp2-cre)2Mpin/?
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slit2^tm1.1Ics mutation (0 available); any Slit2 mutation (88 available)
Tg(Pcp2-cre)2Mpin mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal Purkinje cell dendrite morphology ( J:221288 )

• brain injections of rAAV8 virus expressing cre

• increase in overlaps of Purkinji Cell dendritic branches

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24