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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pelotm2Imad
targeted mutation 1, Ibrahim M Adham
MGI:5705245
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Pelotm1Imad/Pelotm2Imad involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5705410
cn2
 		Pelotm2Imad/Pelotm2Imad
Tg(EIIa-cre)C5379Lmgd/? 		involves: 129S1/Sv * 129X1/SvJ * FVB/N MGI:5705483


Genotype
MGI:5705410
ht1
Allelic
Composition		 Pelotm1Imad/Pelotm2Imad
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pelotm1Imad mutation (0 available); any Pelo mutation (15 available)
Pelotm2Imad mutation (0 available); any Pelo mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:228122 )
• compound heterozygotes, having one functional allele, appear normal and are fertile




Genotype
MGI:5705483
cn2
Allelic
Composition		 Pelotm2Imad/Pelotm2Imad
Tg(EIIa-cre)C5379Lmgd/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pelotm2Imad mutation (0 available); any Pelo mutation (15 available)
Tg(EIIa-cre)C5379Lmgd mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:228122 )
• genotyping more than 100 embryos from intercrosses of EIIa-cre hemizyogus floxed heterozygotes found no null homozygotes at E8.5 indicating complete embryonic lethality of post-cre null allele




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory