homeostasis/metabolism
• mild hypophosphatemia
• however, mice do not display hypercalcemia
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renal/urinary system
N |
• kidney weight and morphology appears normal at 4 months of age under normal physiologic conditions and circulating markers of kidney function, BUN, and plasma creatinine concentrations are normal
• mice exhibit a similar level of renal failure induced by ischemia/reperfusion and similar level of renal damage induced by FA injection as controls
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