All Phenotypes Engase<tm1Tasuz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Engase^tm1Tasuz
targeted mutation 1, Tadashi Suzuki
MGI:5705598

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Engase^tm1Tasuz/Engase^tm1Tasuz Ngly1^tm1.1Tasuz/Ngly1^tm1.1Tasuz	B6.Cg-Engase^tm1Tasuz Ngly1^tm1.1Tasuz	MGI:5896601

Allelic Composition	Engase^tm1Tasuz/Engase^tm1Tasuz Ngly1^tm1.1Tasuz/Ngly1^tm1.1Tasuz
Genetic Background	B6.Cg-Engase^tm1Tasuz Ngly1^tm1.1Tasuz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Engase^tm1Tasuz mutation (1 available); any Engase mutation (26 available)
Ngly1^tm1.1Tasuz mutation (1 available); any Ngly1 mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

limb grasping ( J:307684 )

cellular

cellular phenotype ( J:217663 )

N	• dysregulation of the endoplasmic reticulum (ER)-associated degradation (ERAD) process observed in Ngly1^tm1.1Tasuz homozygous mouse embryonic fibroblasts is restored

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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