Phenotypes associated with this allele

• Allele Symbol: Tg(Slc5a7)1Rbl
• Allele Name: transgene insertion 1, Randy D Blakely
• Allele ID: MGI:5708106
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Slc5a7)1Rbl/?	involves: C57BL/6J	MGI:5708682

Genotype
MGI:5708682

tg1

• Allelic Composition: Tg(Slc5a7)1Rbl/?
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased anxiety-related response ( J:228637 )

• reduced time in open arms of elevated plus maze and increased time in closed arms

• reduction in alternate arm choices in the Y-maze

increased locomotor activity ( J:228637 )

• increased horizontal activity in open field test, vertical activity is similar to controls

• increased speeds on treadmill test, however, strength is not increased

homeostasis/metabolism

increased acetylcholine level ( J:228637 )

• elevated acetylcholine levels in all brain regions

• increased levels are not the result of changes in acetylcholinesterase or choline acetyltransferase activity

enhanced exercise endurance ( J:228637 )

• increased mean endurance time on treadmill test as compared to wild-type