Phenotypes associated with this allele

• Allele Symbol: Gpx4^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5708166
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gpx4^tm1.1(KOMP)Vlcg/Gpx4^tm1.1(KOMP)Vlcg	C57BL/6N-Gpx4^tm1.1(KOMP)Vlcg/MbpMmucd	MGI:6325145
hm2	Gpx4^tm1.1(KOMP)Vlcg/Gpx4^tm1.1(KOMP)Vlcg	C57BL/6N-Gpx4^tm1.1(KOMP)Vlcg/Ucd	MGI:6288499
ht3	Gpx4^tm1.1(KOMP)Vlcg/Gpx4^+	C57BL/6N-Gpx4^tm1.1(KOMP)Vlcg/MbpMmucd	MGI:6325144

Genotype
MGI:6325145

hm1

• Allelic Composition: Gpx4^{tm1.1(KOMP)Vlcg}/Gpx4^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Gpx4^{tm1.1(KOMP)Vlcg}/MbpMmucd
• Cell Lines: 13536A-B6

Data Sources

IMPC Data for Gpx4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6288499

hm2

• Allelic Composition: Gpx4^{tm1.1(KOMP)Vlcg}/Gpx4^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Gpx4^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 13536A-B6

Data Sources

IMPC Data for Gpx4

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

Genotype
MGI:6325144

ht3

• Allelic Composition: Gpx4^{tm1.1(KOMP)Vlcg}/Gpx4⁺
• Genetic Background: C57BL/6N-Gpx4^{tm1.1(KOMP)Vlcg}/MbpMmucd
• Cell Lines: 13536A-B6

Data Sources

IMPC Data for Gpx4

reproductive system

hydrometra ( J:211773 )

♀

IMPC - UCD