Phenotypes associated with this allele

• Allele Symbol: Dnm2^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5708178
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnm2^tm1.1(KOMP)Vlcg/Dnm2^tm1.1(KOMP)Vlcg	C57BL/6N-Dnm2^tm1.1(KOMP)Vlcg/Ucd	MGI:5767640
ht2	Dnm2^tm1.1(KOMP)Vlcg/Dnm2^+	C57BL/6N-Dnm2^tm1.1(KOMP)Vlcg/Ucd	MGI:6262304

Genotype
MGI:5767640

hm1

• Allelic Composition: Dnm2^{tm1.1(KOMP)Vlcg}/Dnm2^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Dnm2^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 16350A-G11

Data Sources

IMPC Data for Dnm2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6262304

ht2

• Allelic Composition: Dnm2^{tm1.1(KOMP)Vlcg}/Dnm2⁺
• Genetic Background: C57BL/6N-Dnm2^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 16350A-G11

Data Sources

IMPC Data for Dnm2

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - UCD

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - UCD

nervous system

small superior vagus ganglion ( J:211773 )

♀

IMPC - UCD

reproductive system

enlarged uterus ( J:211773 )

♀

IMPC - UCD

hydrometra ( J:211773 )

♀

IMPC - UCD