Phenotypes associated with this allele

• Allele Symbol: Kti12^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5708227
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kti12^tm1.1(KOMP)Vlcg/Kti12^tm1.1(KOMP)Vlcg	C57BL/6N-Kti12^tm1.1(KOMP)Vlcg/J	MGI:6262772
ht2	Kti12^tm1.1(KOMP)Vlcg/Kti12^+	C57BL/6N-Kti12^tm1.1(KOMP)Vlcg/J	MGI:6461395

Genotype
MGI:6262772

hm1

• Allelic Composition: Kti12^{tm1.1(KOMP)Vlcg}/Kti12^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Kti12^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 16791A-G4

Data Sources

IMPC Data for Kti12

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6461395

ht2

• Allelic Composition: Kti12^{tm1.1(KOMP)Vlcg}/Kti12⁺
• Genetic Background: C57BL/6N-Kti12^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 16791A-G4

Data Sources

IMPC Data for Kti12

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - JAX

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - JAX

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - JAX

decreased bone mineral density ( J:211773 )

♂

IMPC - JAX