Phenotypes associated with this allele

• Allele Symbol: Cyp27a1^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5708271
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyp27a1^tm1.1(KOMP)Vlcg/Cyp27a1^tm1.1(KOMP)Vlcg	C57BL/6N-Cyp27a1^tm1.1(KOMP)Vlcg/Ucd	MGI:5797463

Genotype
MGI:5797463

hm1

• Allelic Composition: Cyp27a1^{tm1.1(KOMP)Vlcg}/Cyp27a1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Cyp27a1^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 11561A-F9

Data Sources

IMPC Data for Cyp27a1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

enlarged heart ( J:211773 )

♀

IMPC - UCD

decreased heart rate ( J:211773 )

IMPC - UCD

prolonged RR interval ( J:211773 )

IMPC - UCD

shortened QRS complex duration ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♀

IMPC - UCD

increased lean body mass ( J:211773 )

IMPC - UCD

increased liver weight ( J:211773 )

♂

IMPC - UCD

hematopoietic system

decreased mean platelet volume ( J:211773 )

IMPC - UCD

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - UCD

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - UCD

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - UCD

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - UCD

improved glucose tolerance ( J:211773 )

IMPC - UCD

liver/biliary system

increased liver weight ( J:211773 )

♂

IMPC - UCD