Phenotypes associated with this allele

• Allele Symbol: Rnf213^tm1.1Kure
• Allele Name: targeted mutation 1.1, Shigeo Kure
• Allele ID: MGI:5708305
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf213^tm1.1Kure/Rnf213^tm1.1Kure	Not Specified	MGI:5749136

Genotype
MGI:5749136

hm1

• Allelic Composition: Rnf213^tm1.1Kure/Rnf213^tm1.1Kure
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal physiological neovascularization ( J:218591 )

• mice exhibit enhanced angiogenesis after femoral artery ligation compared to wild-type mice

homeostasis/metabolism

decreased susceptibility to injury ( J:218591 )

• blood flow recovery in the ischemic limb is improved in mutants, and mice exhibit milder ambulatory impairments and enhanced angiogenesis after femoral artery ligation compared to wild-type mice

• however, mice do not exhibit differences in infarct volume, edema formation or angiogenesis after transient middle cerebral artery occlusion compared to wild-type mice