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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Prnp-MAPT)#Lgn
transgene insertion, Li Gan
MGI:5708386
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Prnp-MAPT)#Lgn/0 involves: C57BL/6 * FVB/N MGI:5829784


Genotype
MGI:5829784
tg1
Allelic
Composition		 Tg(Prnp-MAPT)#Lgn/0
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
astrocytosis ( J:230252 )
• astrogliosis in the dentate gyrus
• however, mice do not show tau accumulation in hippocampal mossy fibers, normal long term potentiation and synaptic plasticity in the hippocampus, and normal pattern separation memory in an object-context discrimination test




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory