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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Daotm1Ttsu
targeted mutation 1, Takashi Tsukamoto
MGI:5708529
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Daotm1Ttsu/Daotm1Ttsu 129S/SvEv-Daotm1Ttsu MGI:5708535


Genotype
MGI:5708535
hm1
Allelic
Composition		 Daotm1Ttsu/Daotm1Ttsu
Genetic
Background		 129S/SvEv-Daotm1Ttsu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Daotm1Ttsu mutation (0 available); any Dao mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased serine level ( J:228710 )
• increased brain D-serine levels
increased circulating serine level ( J:228710 )
• increased basal plasma D-serine levels
• D-serine levels are increased following administration of oral D-serine

behavior/neurological
increased anxiety-related response ( J:228710 )
• in the open-field test, mice exhibit decreased center path compared with wild-type mice
• however, mice do not exhibit impairment in an elevated-plus maze test




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory