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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kdm6btm1.1Rfw
targeted mutation 1.1, Rong-fu Wang
MGI:5708545
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kdm6btm1.1Rfw/Kdm6btm1.1Rfw Not Specified MGI:5760225


Genotype
MGI:5760225
hm1
Allelic
Composition		 Kdm6btm1.1Rfw/Kdm6btm1.1Rfw
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6btm1.1Rfw mutation (0 available); any Kdm6b mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality ( J:228713 )
• mice die shortly after birth due to lung dysfunction

cellular
increased cell proliferation ( J:228713 )
• mouse embryonic fibroblasts (MEFs) grow faster than wild-type cells and exhibit reduced cellular senescence

respiratory system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory