Phenotypes associated with this allele

• Allele Symbol: Kdm6b^tm1.1Rfw
• Allele Name: targeted mutation 1.1, Rong-fu Wang
• Allele ID: MGI:5708545
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kdm6b^tm1.1Rfw/Kdm6b^tm1.1Rfw	Not Specified	MGI:5760225

Genotype
MGI:5760225

hm1

• Allelic Composition: Kdm6b^tm1.1Rfw/Kdm6b^tm1.1Rfw
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality ( J:228713 )

• mice die shortly after birth due to lung dysfunction

cellular

increased cell proliferation ( J:228713 )

• mouse embryonic fibroblasts (MEFs) grow faster than wild-type cells and exhibit reduced cellular senescence

respiratory system

abnormal respiratory system physiology ( J:228713 )

• lung dysfunction