Analysis Tools
growth/size/body
weight loss
(
J:220560
)
|
• body wt is similar to controls at 6 weeks of age
• decrease in body weight as mice on a normal diet age
|
behavior/neurological
| N |
• food intake is similar to controls
|
homeostasis/metabolism
| N |
• plasma insulin, triglyceride, and free fatty acids are all normal
• glucose tolerance and insulin tolerance are normal at 16 weeks of age
|
|
• plasma glucose is slightly elevated
|
|
• at 9 months
|
|
• significantly reduced hepatic triglyceride levels at 1 year of age
|
adipose tissue
|
• at 14 weeks
|
|
• smaller adipocytes in epididymal fat pad
|
|
• epididymal fat pad reduced at 14 weeks of age
• fewer inflammatory cells in epididymal adipose tissue at 1 year and fat mass is reduced
|
liver/biliary system
|
• significantly reduced hepatic triglyceride levels at 1 year of age
|
|
• reduced hepatic steatosis relative to controls at 1 year of age
|
integument
|
• at 14 weeks
|
