Phenotypes associated with this allele

• Allele Symbol: Arhgap29^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5749747
• Summary: 4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgap29^em1(IMPC)J/Arhgap29^em1(IMPC)J	C57BL/6NJ-Arhgap29^em1(IMPC)J/J	MGI:6150841
hm2	Arhgap29^em1(IMPC)J/Arhgap29^em1(IMPC)J	C57BL/6NJ-Arhgap29^em1(IMPC)J/J	MGI:6261894
ht3	Arhgap29^em1(IMPC)J/Arhgap29^+	C57BL/6NJ-Arhgap29^em1(IMPC)J/J	MGI:6150842
ht4	Arhgap29^em1(IMPC)J/Arhgap29^+	C57BL/6NJ-Arhgap29^em1(IMPC)J/J	MGI:6261893

Genotype
MGI:6150841

hm1

• Allelic Composition: Arhgap29^em1(IMPC)J/Arhgap29^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Arhgap29^em1(IMPC)J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:257248 )

• no homozygotes are identified in embryos from heterozygous intercrosses as early as E8.5

Genotype
MGI:6261894

hm2

• Allelic Composition: Arhgap29^em1(IMPC)J/Arhgap29^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Arhgap29^em1(IMPC)J/J

Data Sources

IMPC Data for Arhgap29

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6150842

ht3

• Allelic Composition: Arhgap29^em1(IMPC)J/Arhgap29⁺
• Genetic Background: C57BL/6NJ-Arhgap29^em1(IMPC)J/J

craniofacial

palatal shelf fusion with tongue or mandible ( J:257248 )

abnormal oral epithelium morphology ( J:257248 )

• intraoral epithelial adhesions are found at E14.5, but fewer than are found in mice heterozygous for the em1Murr allele

digestive/alimentary system

palatal shelf fusion with tongue or mandible ( J:257248 )

abnormal oral epithelium morphology ( J:257248 )

• intraoral epithelial adhesions are found at E14.5, but fewer than are found in mice heterozygous for the em1Murr allele

growth/size/body

palatal shelf fusion with tongue or mandible ( J:257248 )

abnormal oral epithelium morphology ( J:257248 )

• intraoral epithelial adhesions are found at E14.5, but fewer than are found in mice heterozygous for the em1Murr allele

Genotype
MGI:6261893

ht4

• Allelic Composition: Arhgap29^em1(IMPC)J/Arhgap29⁺
• Genetic Background: C57BL/6NJ-Arhgap29^em1(IMPC)J/J

Data Sources

IMPC Data for Arhgap29

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - JAX

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - JAX