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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fnip2tm1.2Lss
targeted mutation 1.2, Laura S Schmidt
MGI:5749954
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fnip2tm1.2Lss/Fnip2tm1.2Lss involves: C57BL/6 MGI:5897112
cx2
 		Fnip1tm1.2Baba/Fnip1+
Fnip2tm1.2Lss/Fnip2tm1.2Lss 		involves: C57BL/6 MGI:5897118


Genotype
MGI:5897112
hm1
Allelic
Composition		 Fnip2tm1.2Lss/Fnip2tm1.2Lss
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fnip2tm1.2Lss mutation (0 available); any Fnip2 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:220672 )
• no phenotypes affecting lifespan are detected




Genotype
MGI:5897118
cx2
Allelic
Composition		 Fnip1tm1.2Baba/Fnip1+
Fnip2tm1.2Lss/Fnip2tm1.2Lss
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fnip1tm1.2Baba mutation (0 available); any Fnip1 mutation (60 available)
Fnip2tm1.2Lss mutation (0 available); any Fnip2 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased kidney tumor incidence ( J:220672 )
• develop kidney cancer
• develop a variety of lesions with hybrid oncocytic tumors being most common

renal/urinary system
increased kidney tumor incidence ( J:220672 )
• develop kidney cancer
• develop a variety of lesions with hybrid oncocytic tumors being most common

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Birt-Hogg-Dube syndrome DOID:0050676 OMIM:135150
 J:220672




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory