Phenotypes associated with this allele

• Allele Symbol: Melk^tm1.1Flev
• Allele Name: targeted mutation 1, Fred Levine
• Allele ID: MGI:5750925
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Melk^tm1.1Flev/Melk^tm1.1Flev	Not Specified	MGI:5750928

Genotype
MGI:5750928

hm1

• Allelic Composition: Melk^tm1.1Flev/Melk^tm1.1Flev
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:228782 )

N • untreated mice exhibit normal islet and duct morphology

abnormal pancreas regeneration ( J:228782 )

• following pancreatic duct ligation plus alloxan, mice exhibit increased duct density and decreased average size of each duct compared with wild-type mice

• however, injured mice exhibit normal total number of duct cells and numbers of beta- and alpha-cells

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:228782 )

N • untreated mice are euglycemic