All Phenotypes Runx2<tm1.1Hkiy> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Runx2^tm1.1Hkiy
targeted mutation 1.1, Hiroshi Kiyono
MGI:5750985

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Runx2^tm1.1Hkiy/Runx2^tm1.1Hkiy	involves: 129P2/OlaHsd * C57BL/6	MGI:5770599

Allelic Composition	Runx2^tm1.1Hkiy/Runx2^tm1.1Hkiy
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx2^tm1.1Hkiy mutation (0 available); any Runx2 mutation (44 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:223410 )

N	• homozygotes display normal survival relative to wild-type controls, suggesting that the neonatal lethality observed in Runx2^tm1Hkiy homozygotes is completely rescued by the neo cassette deletion

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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