Analysis Tools
behavior/neurological
 |
• males show lower acoustic startle response
|
|
• mice exhibit reduction of 2-paw strength
|
|
• some mice exhibit abnormal gait
|
hypoalgesia
(
J:221990
)
|
• mice exhibit hypoalgesia in the hot plate test
|
hematopoietic system
|
|
• males exhibit slightly higher frequency of CD19+ cells
|
immune system
|
• mice exhibit a higher proportion of CD44 expressing cells and lower proportion of CD62L within the T cell cluster
|
|
|
• males exhibit slightly higher frequency of CD19+ cells
|
nervous system
respiratory system
 |
• females show slightly lower respiratory rates, slightly lower tidal volumes and minute ventilation volumes at rest
• however, mice show normal adaptation to activity
|
|
|
• females show slightly lower minute ventilation volumes at rest
|
reproductive system
| N |
• mice are fertile
|
mortality/aging
| N |
• mice are viable, are obtained in the expected Mendelian ratio and have a lifespan of 15-17 months
|
