Phenotypes associated with this allele

• Allele Symbol: Prdm13^tm1.1Tfur
• Allele Name: targeted mutation 1.1, Takahisa Furukawa
• Allele ID: MGI:5752205
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Prdm13^tm1.1Tfur/Prdm13^tm1.1Tfur Tg(Dkk3-cre)D9Tfur/0	involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N	MGI:5780207

Genotype
MGI:5780207

cn1

• Allelic Composition: Prdm13^tm1.1Tfur/Prdm13^tm1.1Tfur; Tg(Dkk3-cre)D9Tfur/0
• Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

decreased amacrine cell number ( J:222242 )

• specific reduction in the number of GABAergic or glycinergic amacrine cells at P14

abnormal retina inner plexiform layer morphology ( J:222242 )

• loss of the S2/S3 border neurite bundle labeled by anti-Calretinin antibodies in the IPL at P14

behavior/neurological

abnormal optokinetic reflex ( J:222242 )

• at 2 months of age, mice exhibit higher responses to visual stimuli in initial optokinetic responses with a broader range of spatial and temporal frequencies than those observed in controls

nervous system

decreased amacrine cell number ( J:222242 )

• specific reduction in the number of GABAergic or glycinergic amacrine cells at P14