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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Raet1dem1Dhr
endonuclease-mediated mutation 1, David H Raulet
MGI:5752307
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Raet1dem1Dhr/Raet1dem1Dhr
Raet1eem1Dhr/Raet1eem1Dhr 		involves: C57BL/6 MGI:5776122


Genotype
MGI:5776122
cx1
Allelic
Composition		 Raet1dem1Dhr/Raet1dem1Dhr
Raet1eem1Dhr/Raet1eem1Dhr
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Raet1dem1Dhr mutation (0 available); any Raet1d mutation (11 available)
Raet1eem1Dhr mutation (0 available); any Raet1e mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased natural killer cell mediated cytotoxicity ( J:221188 )
• peritoneal NK cells exhibit increased functional responses ex vivo to YAC-1 compared with wild-type cells

hematopoietic system
increased natural killer cell mediated cytotoxicity ( J:221188 )
• peritoneal NK cells exhibit increased functional responses ex vivo to YAC-1 compared with wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory