Phenotypes associated with this allele

• Allele Symbol: Scyl2^tm1.2Spel
• Allele Name: targeted mutation 1.2, Stephane Pelletier
• Allele ID: MGI:5752502
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scyl2^tm1.2Spel/Scyl2^tm1.2Spel	involves: 129S6/SvEvTac * C57BL/6	MGI:5752575

Genotype
MGI:5752575

hm1

• Allelic Composition: Scyl2^tm1.2Spel/Scyl2^tm1.2Spel
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:225808 )

• most mice die within 24 hours of birth

• however, mice that survive are present at weaning

behavior/neurological

abnormal behavior ( J:225808 )

• sensory-motor deficits and abnormal behaviors in mice that survive beyond the neonatal period

absent gastric milk in neonates ( J:225808 )

limb grasping ( J:225808 )

• in mice that survive beyond the neonatal period

growth/size/body

postnatal growth retardation ( J:225808 )

• in mice that survive beyond the neonatal period

craniofacial

craniofacial phenotype ( J:225808 )

N • mice exhibit normal craniofacial morphology