Phenotypes associated with this allele

• Allele Symbol: Gtf2e2^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5752549
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gtf2e2^tm1b(EUCOMM)Wtsi/Gtf2e2^tm1b(EUCOMM)Wtsi	C57BL/6N-Gtf2e2^tm1b(EUCOMM)Wtsi/H	MGI:5767681
ht2	Gtf2e2^tm1b(EUCOMM)Wtsi/Gtf2e2^+	C57BL/6N-Gtf2e2^tm1b(EUCOMM)Wtsi/H	MGI:6461316

Genotype
MGI:5767681

hm1

• Allelic Composition: Gtf2e2^{tm1b(EUCOMM)Wtsi}/Gtf2e2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Gtf2e2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0784_2_C01

Data Sources

IMPC Data for Gtf2e2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6461316

ht2

• Allelic Composition: Gtf2e2^{tm1b(EUCOMM)Wtsi}/Gtf2e2⁺
• Genetic Background: C57BL/6N-Gtf2e2^{tm1b(EUCOMM)Wtsi}/H
• Cell Lines: EPD0784_2_C01

Data Sources

IMPC Data for Gtf2e2

hematopoietic system

increased mean platelet volume ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

IMPC - HAR