Phenotypes associated with this allele

• Allele Symbol: Nr1d2^tm1.1Pbrc
• Allele Name: targeted mutation 1.1, Pennington Biomedical Research Center
• Allele ID: MGI:5752902
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nr1d2^tm1.1Pbrc/Nr1d2^tm1.1Pbrc	involves: C57BL/6J	MGI:5755520

Genotype
MGI:5755520

hm1

• Allelic Composition: Nr1d2^tm1.1Pbrc/Nr1d2^tm1.1Pbrc
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired behavioral response to xenobiotic ( J:225389 )

• in the marble burying assay, mice treated with the synthetic REV-ERB agonist SR9011 fail to display an anxiolytic response and bury a similar number of marbles relative to vehicle-treated mice

increased anxiety-related response ( J:225389 )

• in the marble burying assay, mice bury significantly more marbles than wild-type controls, indicating increased anxiety-like behavior