All Phenotypes Dnajc7<tm1.2Neg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dnajc7^tm1.2Neg
targeted mutation 1, Masahiko Negishi
MGI:5752955

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnajc7^tm1.2Neg/Dnajc7^tm1.2Neg	involves: 129S/SvEv * C57BL/6 * CBA	MGI:5753052

Allelic Composition	Dnajc7^tm1.2Neg/Dnajc7^tm1.2Neg
Genetic Background	involves: 129S/SvEv * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnajc7^tm1.2Neg mutation (0 available); any Dnajc7 mutation (110 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Steatotic liver and increased cholesterol levels in Dnajc7^tm1.2Neg/Dnajc7^tm1.2Neg males

homeostasis/metabolism

increased circulating cholesterol level ( J:225381 )

• in male mice

liver/biliary system

hepatic steatosis ( J:225381 )

• in male mice in response to 24 h fasting

• however, serum triglyceride levels are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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