All Phenotypes Adnp2<em3(IMPC)Tcp> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Adnp2^em3(IMPC)Tcp
endonuclease-mediated mutation 3, The Centre for Phenogenomics
MGI:5754578

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adnp2^em3(IMPC)Tcp/Adnp2^em3(IMPC)Tcp	C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp	MGI:6261817
ht2	Adnp2^em3(IMPC)Tcp/Adnp2⁺	C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp	MGI:6394239

Allelic Composition	Adnp2^em3(IMPC)Tcp/Adnp2^em3(IMPC)Tcp
Genetic Background	C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adnp2^em3(IMPC)Tcp mutation (2 available); any Adnp2 mutation (53 available)

Data Sources

IMPC Data for Adnp2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

IMPC - TCP

hyperactivity ( J:211773 )

IMPC - TCP

growth/size/body

decreased body length ( J:211773 )

IMPC - TCP

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

IMPC - TCP

decreased circulating total protein level ( J:211773 )

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

IMPC - TCP

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - TCP

reproductive system

abnormal uterus morphology ( J:211773 )

IMPC - TCP

respiratory system

abnormal lung morphology ( J:211773 )

IMPC - TCP

skeleton

short tibia ( J:211773 )

IMPC - TCP

abnormal bone structure ( J:211773 )

IMPC - TCP

decreased bone mineral content ( J:211773 )

IMPC - TCP

decreased bone mineral density ( J:211773 )

IMPC - TCP

Allelic Composition	Adnp2^em3(IMPC)Tcp/Adnp2⁺
Genetic Background	C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adnp2^em3(IMPC)Tcp mutation (2 available); any Adnp2 mutation (53 available)

Data Sources

IMPC Data for Adnp2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

absent adrenal gland ( J:211773 )

IMPC - TCP

small adrenal glands ( J:211773 )

IMPC - TCP

abnormal thymus morphology ( J:211773 )

IMPC - TCP

abnormal ovary morphology ( J:211773 )

IMPC - TCP

hematopoietic system

abnormal thymus morphology ( J:211773 )

IMPC - TCP

small spleen ( J:211773 )

IMPC - TCP

immune system

abnormal thymus morphology ( J:211773 )

IMPC - TCP

small spleen ( J:211773 )

IMPC - TCP

enlarged lymph nodes ( J:211773 )

IMPC - TCP

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - TCP

renal/urinary system

small kidney ( J:211773 )

IMPC - TCP

reproductive system

abnormal ovary morphology ( J:211773 )

IMPC - TCP

small uterus ( J:211773 )

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

IMPC - TCP

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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