Phenotypes associated with this allele

• Allele Symbol: Ino80^tm1.2Jland
• Allele Name: targeted mutation 1.2, Joseph Landry
• Allele ID: MGI:5755269
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ino80^tm1.2Jland/Ino80^tm1.2Jland	B6.129(C)-Ino80^tm1.2Jland	MGI:5755273

Genotype
MGI:5755273

hm1

• Allelic Composition: Ino80^tm1.2Jland/Ino80^tm1.2Jland
• Genetic Background: B6.129(C)-Ino80^tm1.2Jland

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:229516 )

• E7.5 embryos exhibit a loss of structural integrity, but are intact at E6.5

embryo

absent anterior visceral endoderm ( J:229516 )

• E6.5 embryos lack an anterior visceral endoderm (AVE)

• however, the primitive endoderm (PrE) and epiblast are normal in E4.5 embryos

absent distal visceral endoderm ( J:229516 )

• E5.5 embryos fail to specify a distal visceral endoderm (DVE)

• however, the primitive endoderm (PrE) and epiblast are normal in E4.5 embryos