All Phenotypes Gria1<tm1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gria1^tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:5760004

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gria1^tm1Lex/Gria1^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6	MGI:5760005

Allelic Composition	Gria1^tm1Lex/Gria1^tm1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria1^tm1Lex mutation (1 available); any Gria1 mutation (65 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased locomotor activity ( J:82809 )

• homozygous mutant mice exhibit markedly increased locomotor activity during open field testing compared to same-sex wild-type littermates and historical means

hematopoietic system

decreased glycosylated hemoglobin level ( J:82809 )

• female homozygous mutant mice exhibit decreased median serum HgbA1c levels

homeostasis/metabolism

decreased glycosylated hemoglobin level ( J:82809 )

• female homozygous mutant mice exhibit decreased median serum HgbA1c levels

increased blood urea nitrogen level ( J:82809 )

• homozygous mutants exhibit increased mean serum blood urea nitrogen levels

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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