Phenotypes associated with this allele

• Allele Symbol: Smg6^tm1.2Zqw
• Allele Name: targeted mutation 1.2, Zhao-Qi Wang
• Allele ID: MGI:5763145
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smg6^tm1.2Zqw/Smg6^tm1.2Zqw	involves: 129P2/OlaHsd * C57BL/6 * CBA	MGI:5763152

Genotype
MGI:5763152

hm1

• Allelic Composition: Smg6^tm1.2Zqw/Smg6^tm1.2Zqw
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality at implantation, incomplete penetrance ( J:222980 )

• mice die after implantation

prenatal lethality, complete penetrance ( J:222980 )

• no viable mice are produced

embryo

decreased inner cell mass proliferation ( J:222980 )

• cultured blastocysts fail to grown

embryonic growth retardation ( J:222980 )

• rare embryos are growth retarded at E7.5

growth/size/body

embryonic growth retardation ( J:222980 )

• rare embryos are growth retarded at E7.5

cellular

decreased inner cell mass proliferation ( J:222980 )

• cultured blastocysts fail to grown